Pressure applied to nerves because of a subluxation can affect the proper function of all the organs in your body, and can lead to pain, weakness, and numbness. Click here for the full article *Spinal Manipulation Postepidural Injection for Lumbar and Cervical Radiculopathy: A Retrospective Case Series Journal of Manipulative and Physiological Therapeutics. September 2004. Volume 27. Number 7